Evaluation of one-sample testing of self-obtained vaginal swabs and first catch urine samples separately and in combination for the detection of Chlamydia trachomatis by two amplified DNA assays in women visiting a sexually transmitted disease clinic

Laura van Dommelen; Nicole Dukers-Muijrers; Frank H van Tiel; Elfi E H G Brouwers; Christian J P A Hoebe

doi:10.1097/OLQ.0b013e318205e435

Evaluation of one-sample testing of self-obtained vaginal swabs and first catch urine samples separately and in combination for the detection of Chlamydia trachomatis by two amplified DNA assays in women visiting a sexually transmitted disease clinic

Sex Transm Dis. 2011 Jun;38(6):533-5. doi: 10.1097/OLQ.0b013e318205e435.

Authors

Laura van Dommelen¹, Nicole Dukers-Muijrers, Frank H van Tiel, Elfi E H G Brouwers, Christian J P A Hoebe

Affiliation

¹ Department of Medical Microbiology, Maastricht University Medical Centre, Maastricht, The Netherlands. [email protected]

PMID: 21217415
DOI: 10.1097/OLQ.0b013e318205e435

Abstract

This study evaluates the performance of self-obtained vaginal swabs (SVS)/first-catch urine (FCU) combination samples in comparison to testing FCU or SVS alone. The Chlamydia trachomatis detection rate for the SVS, FCU, and SVS/FCU combination were 94%, 90%, and 94%, respectively. Self-obtained vaginal swabs are therefore the specimen of choice for Chlamydia trachomatis Nucleic Acid Amplification Tests in females.

Publication types

Evaluation Study

MeSH terms

Ambulatory Care Facilities
Chlamydia Infections / diagnosis*
Chlamydia Infections / microbiology
Chlamydia Infections / prevention & control
Chlamydia Infections / urine
Chlamydia trachomatis / genetics
Chlamydia trachomatis / isolation & purification*
Female
Humans
Nucleic Acid Amplification Techniques / methods*
Polymerase Chain Reaction
Self Care*
Sensitivity and Specificity
Sexually Transmitted Diseases / prevention & control
Specimen Handling / methods*
Urine / microbiology*
Vagina / microbiology*