Abstract
A-75 year-old man, diagnosed as ascending colon cancer with large bowel obstruction, multiple hepatic, lunge metastases and peritoneal dissemination, was treated with neoadjuvant chemotherapy (FOLFOX4: 2 courses) and subsequent ileocecal resection. Postoperative systemic chemotherapy with hepatic arterial infusion (HAI) of 5-FU was performed in the following fashion: FOLFOX4, FOLFIRI with or without bevacizumab or cetuximab was administered every 4 weeks and a weekly HAI twice every 4 weeks. By those treatments, the patient could maintain a 30-month long NC effect and a good performance status.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Angiogenesis Inhibitors / administration & dosage
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Antibodies, Monoclonal / administration & dosage
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Antibodies, Monoclonal, Humanized
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Antineoplastic Agents / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Bevacizumab
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Camptothecin / administration & dosage
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Camptothecin / analogs & derivatives
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Cetuximab
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Colonic Neoplasms / drug therapy*
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Colonic Neoplasms / pathology
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Colonic Neoplasms / surgery
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Fluorouracil / administration & dosage
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Hepatic Artery
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Humans
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Infusions, Intra-Arterial
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Leucovorin / administration & dosage
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Liver Neoplasms / secondary
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Lung Neoplasms / secondary
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Male
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Neoadjuvant Therapy
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Organoplatinum Compounds / administration & dosage
Substances
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Angiogenesis Inhibitors
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Antineoplastic Agents
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Organoplatinum Compounds
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Bevacizumab
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Cetuximab
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Leucovorin
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Fluorouracil
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Camptothecin
Supplementary concepts
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Folfox protocol
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IFL protocol