Abstract
A 63-year-old female was diagnosed as descending colon cancer with severe liver dysfunction caused by multiple liver metastases. Her performance status (PS) was 3 because of liver dysfunction and high fever. Initially, hepatic arterial infusion (HAI) chemotherapy was started to reduce the size of metastatic tumors and to prevent a liver failure. After 10 courses of HAI chemotherapy, she recovered from liver dysfunction, and CapeOX plus bevacizumab regimen was started. A partial response of metastatic liver tumors was observed after 8 cycles of this regimen and metastatic lung tumors were disappeared. The patient was alive after 12 months with PS 0 and CapeOX was continued.
MeSH terms
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Angiogenesis Inhibitors / administration & dosage
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Antibodies, Monoclonal / administration & dosage
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Antibodies, Monoclonal, Humanized
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Antineoplastic Agents / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Bevacizumab
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Colonic Neoplasms / drug therapy*
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Colonic Neoplasms / pathology
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Female
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Hepatic Artery
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Humans
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Infusions, Intra-Arterial
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Liver Neoplasms / secondary*
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Middle Aged
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Organoplatinum Compounds / administration & dosage
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Oxaliplatin
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Treatment Outcome
Substances
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Angiogenesis Inhibitors
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Antineoplastic Agents
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Organoplatinum Compounds
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Oxaliplatin
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Bevacizumab