A FAK-PI-3K-mTOR axis is required for Wnt-Myc driven intestinal regeneration and tumorigenesis

Cell Cycle. 2011 Jan 15;10(2):173-5. doi: 10.4161/cc.10.2.14350. Epub 2011 Jan 15.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Adenomatous Polyposis Coli Protein / genetics
  • Adenomatous Polyposis Coli Protein / metabolism
  • Animals
  • Focal Adhesion Kinase 1 / genetics
  • Focal Adhesion Kinase 1 / metabolism*
  • Focal Adhesion Kinase 1 / physiology
  • Intestinal Mucosa / metabolism
  • Intestinal Mucosa / physiology*
  • Intestinal Neoplasms / enzymology
  • Intestinal Neoplasms / etiology*
  • Intestinal Neoplasms / metabolism
  • Mice
  • Mice, Knockout
  • Phosphatidylinositol 3-Kinases / metabolism*
  • Proto-Oncogene Proteins c-myc / metabolism*
  • Signal Transduction
  • TOR Serine-Threonine Kinases / metabolism*
  • Wnt Proteins / metabolism*

Substances

  • Adenomatous Polyposis Coli Protein
  • Proto-Oncogene Proteins c-myc
  • Wnt Proteins
  • mTOR protein, mouse
  • Focal Adhesion Kinase 1
  • TOR Serine-Threonine Kinases