To clarify responses of soil ecological stoichiometry in wetland to human disturbance, the ecological stoichiometry characteristics of carbon, nitrogen and phosphorus elements of soil in Phragmites australis marsh, grassland, flat breed aquatics, cropland, pond aquaculture after human disturbance and abandoned cropland after human disturbance restoration in Minjiang River estuary were analyzed. The results showed: averaged values of C/N, C/P, N/P ratios were declined as the human disturbance increment, which appeared that Phragmites australis marsh, grassland (lower human disturbance, 25.53, 156.06, 6.11 and 27.58, 158.99, 5.78) were bigger than flat breed aquatics (medium human disturbance, 25.02, 96.90, 3.87), and flat breed aquatics (medium human disturbance) were bigger than cropland, pond aquaculture (higher human disturbance, 17.55, 46.19, 2.65 and 22.30, 57.51, 2.62). Compared with cropland, C/N, C/P, N/P ratios in abandoned cropland (human disturbance restoration) were (19.95, 63.81, 3.18) higher. The influencing factors were changed with the human disturbance intensity. Soil C/N ratios showed relatively small variation between different human disturbance and soil depth, while C/P and N/P ratios showed a high heterogeneity. The ratio of carbon to nutrition had preferable indication for carbon storage.