A rapid and efficient access to diaryldibenzo[b,f][1,5]diazocines

Org Lett. 2011 Feb 18;13(4):709-11. doi: 10.1021/ol102957c. Epub 2011 Jan 13.

Abstract

2-Benzoylbenzoyl azides undergo facile cyclization under acidic conditions to give substituted dibenzo[b,f][1,5]-diazocines in good yields. This approach shortens the synthetic steps toward these compounds as compared with conventional methods. The mechanism of the diazocine synthesis is assumed to proceed by an unprecedented intermolecular [2 + 2] cyclization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azides / chemistry*
  • Azocines / chemical synthesis*
  • Azocines / chemistry
  • Benzophenones / chemistry*
  • Catalysis
  • Cyclization
  • Molecular Structure

Substances

  • Azides
  • Azocines
  • Benzophenones
  • 2-benzoylbenzoic acid