Highly diastereo- and enantio-selective epoxidation of secondary allylic alcohols catalyzed by styrene monooxygenase

Chem Commun (Camb). 2011 Mar 7;47(9):2610-2. doi: 10.1039/c0cc04360e. Epub 2011 Jan 13.

Abstract

Enantiomerically enriched glycidol derivatives with contiguous stereogenic centers were obtained in a highly diastereo- and enantio-selective epoxidation catalyzed with the styrene monooxygenase StyAB2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocatalysis
  • Catalytic Domain
  • Computer Simulation
  • Epoxy Compounds / chemistry
  • Oxygenases / metabolism*
  • Propanols / chemistry*
  • Stereoisomerism

Substances

  • Epoxy Compounds
  • Propanols
  • allyl alcohol
  • Oxygenases
  • styrene monooxygenase
  • glycidol