An evaluation of the "in vivo" and "in vitro" biological reaction and mechanical features of carbon fibre composites

A Sudanese; G Ciappetti; N Baldini; S Stea; D Ciaroni; D Dallari; A Toni; A Giunti

An evaluation of the "in vivo" and "in vitro" biological reaction and mechanical features of carbon fibre composites

Chir Organi Mov. 1990 Apr-Jun;75(2):171-6.

[Article in English, Italian]

Authors

A Sudanese¹, G Ciappetti, N Baldini, S Stea, D Ciaroni, D Dallari, A Toni, A Giunti

Affiliation

¹ Clinica Ortopedica dell'Università di Bologna, Istituto Ortopedico Rizzoli, Bologna.

PMID: 2126233

Abstract

Tissue reaction to an epoxy resin-carbon fibre composite was tested "in vivo" and "in vitro" in order to evaluate this material as an alternative to metal alloys for clinical use in orthopaedic surgery. While the "in vitro" tests suggest a mild toxic effect of the composite on cells, good biocompatibility "in vivo" was observed when debris are not generated. The mechanical tests compared the composite and stainless steel plates, confirming the expected values for static strength and elastic modulus, revealing, however, the formation of long needles of carbon fibre following breakage of the plate.

Publication types

Comparative Study

MeSH terms

Animals
Bone Plates*
Carbon / chemistry
Carbon / toxicity*
Carbon Fiber
Cells, Cultured / drug effects
Drug Combinations
Epoxy Resins / chemistry
Epoxy Resins / toxicity
Fibroblasts / drug effects
Haplorhini
Materials Testing / methods
Powders
Rabbits
Stress, Mechanical
Time Factors

Substances

Carbon Fiber
Drug Combinations
Epoxy Resins
Powders
Carbon