Abstract
The concomitant use of silver oxide and catalytic amount of TBAF allowed the efficient and chemoselective coupling of readily available 4-chloro- and 4-methyl-2-trimethyl-silyl-pyridines with heteroaromatic and aromatic halides. Based on control experiments, a mechanism involving the formation of a pyridylsilver intermediate and TBAF recycling is postulated.
MeSH terms
-
Allyl Compounds / chemistry
-
Catalysis
-
Cross-Linking Reagents / chemistry
-
Molecular Structure
-
Oxides / chemistry*
-
Pyridines / chemistry*
-
Quaternary Ammonium Compounds / chemistry*
-
Silver Compounds / chemistry*
Substances
-
Allyl Compounds
-
Cross-Linking Reagents
-
Oxides
-
Pyridines
-
Quaternary Ammonium Compounds
-
Silver Compounds
-
disilver oxide
-
tetrabutylammonium
-
pyridine