Palladium-catalyzed carboiodination of alkenes: carbon-carbon bond formation with retention of reactive functionality

J Am Chem Soc. 2011 Feb 16;133(6):1778-80. doi: 10.1021/ja110377q. Epub 2011 Jan 25.

Abstract

We report a palladium-catalyzed carbon-carbon bond-forming reaction between aryl iodides and alkenes. In contrast to traditional cross-coupling reactions, two new bonds are formed, and all of the atoms in the starting materials are incorporated into the product. The use of a palladium catalyst with bulky phosphine ligands is found to be crucial for reactivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • Carbon / chemistry*
  • Catalysis
  • Halogenation*
  • Oxidation-Reduction
  • Palladium / chemistry*

Substances

  • Alkenes
  • Palladium
  • Carbon