Salmonella enterica serotype Gambia with CTX-M-3 and armA resistance markers: nosocomial infections with a fatal outcome

J Clin Microbiol. 2011 Apr;49(4):1676-8. doi: 10.1128/JCM.02127-10. Epub 2011 Jan 26.

Abstract

We report two cases of bacteremia caused by the Salmonella enterica serotype Gambia in our children's hospital, with one fatal outcome. The isolates showed indistinguishable genotypes and infrequent resistance markers: CTX-M-3 extended-spectrum β-lactamase and armA methyltransferase. This is the first report of S. Gambia exhibiting CTX-M-3 and armA markers involved in serious infections.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteremia / microbiology*
  • Bacterial Typing Techniques
  • Cross Infection / microbiology*
  • DNA, Bacterial / genetics
  • Drug Resistance, Bacterial
  • Electrophoresis, Gel, Pulsed-Field
  • Fatal Outcome
  • Female
  • Gambia
  • Genotype
  • Humans
  • Infant
  • Male
  • Molecular Typing
  • Salmonella Infections / microbiology*
  • Salmonella enterica / drug effects*
  • Salmonella enterica / enzymology*
  • Salmonella enterica / genetics
  • Salmonella enterica / isolation & purification
  • beta-Lactamases / genetics*
  • tRNA Methyltransferases / genetics*

Substances

  • DNA, Bacterial
  • tRNA Methyltransferases
  • beta-lactamase CTX-M-3
  • beta-Lactamases