Complete genomic characterization of cell culture adapted human G12P[6] rotaviruses isolated from South Korea

Virus Genes. 2011 Jun;42(3):317-22. doi: 10.1007/s11262-011-0576-x. Epub 2011 Jan 30.

Abstract

Two unusual human rotavirus G12 strains, CAU195 and CAU214, were isolated from female pediatric diarrhea patients under 12 months of age in 2006 using a cell culture system and their full genome sequences were analyzed. The 11 gene segments of both Korean G12 strains were classified as G12-P[6]-R1-C1-M1-I1-A1-N1-T1-E1-H1 genotypes. Notably, the Korean strains were of the same genotypes as previously reported strains isolated from Bangladesh in 2003 (Dhaka12-03), from the United States in 2005-2006 (US6597), and from Germany in 2008 (GER126-08 and GER172-08), suggesting that closely related G12P[6] strains are persistent and widespread.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Cell Culture Techniques
  • Cell Line
  • Female
  • Genome, Viral*
  • Humans
  • Infant
  • Molecular Sequence Data
  • Phylogeny
  • Republic of Korea
  • Rotavirus / classification
  • Rotavirus / genetics*
  • Rotavirus / isolation & purification
  • Rotavirus / physiology
  • Rotavirus Infections / virology*

Associated data

  • GENBANK/EF059916
  • GENBANK/EF059917
  • GENBANK/EF059918
  • GENBANK/EF059919
  • GENBANK/EF059920
  • GENBANK/EF059921
  • GENBANK/EU556221
  • GENBANK/EU556222
  • GENBANK/HQ025973
  • GENBANK/HQ025974
  • GENBANK/HQ025975
  • GENBANK/HQ025976
  • GENBANK/HQ025977
  • GENBANK/HQ025978
  • GENBANK/HQ025979
  • GENBANK/HQ025980
  • GENBANK/HQ025981
  • GENBANK/HQ025982
  • GENBANK/HQ025983
  • GENBANK/HQ025984
  • GENBANK/HQ025985
  • GENBANK/HQ025986