Mutations in bglY, the structural gene for the DNA-binding protein H1, affect expression of several Escherichia coli genes

P Bertin; P Lejeune; C Laurent-Winter; A Danchin

doi:10.1016/0300-9084(90)90008-5

Mutations in bglY, the structural gene for the DNA-binding protein H1, affect expression of several Escherichia coli genes

Biochimie. 1990 Dec;72(12):889-91. doi: 10.1016/0300-9084(90)90008-5.

Authors

P Bertin¹, P Lejeune, C Laurent-Winter, A Danchin

Affiliation

¹ Unité de Régulation de l'Expression Génétique, Université de Louvain, Louvain-la-Neuve, Belgium.

PMID: 2128918
DOI: 10.1016/0300-9084(90)90008-5

Abstract

The protein patterns of a bglY mutant and the isogenic wild-type strains were compared on 2-dimensional gel electrophoresis. The synthesis of at least 36 peptides was affected. This suggests a global but specific role on gene expression for the DNA-binding protein H1.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / genetics*
Bacterial Proteins / isolation & purification
DNA-Binding Proteins / genetics*
DNA-Binding Proteins / isolation & purification
Electrophoresis, Gel, Two-Dimensional
Escherichia coli / genetics*
Gene Expression Regulation, Bacterial
Genes
Genes, Bacterial
Mutation

Substances

Bacterial Proteins
DNA-Binding Proteins
H-NS protein, bacteria