Does a supplementary preoperative breast MRI in patients with invasive lobular breast cancer change primary and secondary surgical interventions?

Ann Surg Oncol. 2011 Aug;18(8):2143-9. doi: 10.1245/s10434-011-1565-y. Epub 2011 Feb 3.

Abstract

Background: We evaluated whether a supplementary preoperative breast MRI in patients with invasive lobular breast cancer (ILC) has changed number and methods of primary and number of secondary surgical interventions.

Materials and methods: This was a retrospective controlled single-center analysis of 178 ILC patients. The 2 study groups consisted of 92 patients with breast MRI (MRI group) and of 86 patients without breast MRI (non-MRI group). We investigated the primary and final surgical procedures and factors that influenced the number of secondary surgical interventions.

Results: A total of 40 primary mastectomies (38%) have been performed in the MRI group, compared with 27 (30%) in the non-MRI group (P = .119).There have been more bilateral surgical interventions in the MRI group (14 vs 3 patients; P = .002). The 2 groups did not differ with respect to secondary surgery rates (P = .429). The MRI and non-MRI group were significantly different with respect to age and breast density (P = .003 and P = .002). Yet, both variables seemed not to influence secondary surgery rates (P = .516 and P = .788, respectively).

Conclusions: The implementation of preoperative breast MRI tended to result in more primary mastectomies and bilateral surgeries and did not seem to decrease the secondary surgery rate.

Publication types

  • Clinical Trial

MeSH terms

  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / surgery*
  • Carcinoma, Ductal, Breast / diagnosis
  • Carcinoma, Ductal, Breast / surgery*
  • Carcinoma, Lobular / diagnosis
  • Carcinoma, Lobular / surgery*
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging*
  • Mammography*
  • Middle Aged
  • Neoplasm Invasiveness
  • Preoperative Care
  • Reoperation*
  • Survival Rate
  • Treatment Outcome