Abstract
An Escherichia coli isolate with New Delhi metallo-beta-lactamase was isolated from a patient with pyelonephritis and prostatitis who returned to Canada after recent hospitalization in India. The patient was successfully treated with ertapenem and fosfomycin. This patient highlights the role of international travel in the spread of antimicrobial drug resistance and blaNDM-1.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Canada
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Carbapenems / pharmacology
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Drug Resistance, Multiple, Bacterial
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Ertapenem
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Escherichia coli / drug effects
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Escherichia coli / enzymology*
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Escherichia coli / genetics
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Escherichia coli / isolation & purification
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Escherichia coli Infections / microbiology*
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Fosfomycin / therapeutic use
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Humans
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India
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Male
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Microbial Sensitivity Tests
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Prostatitis / microbiology*
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Pyelonephritis / microbiology*
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Travel*
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Urine / microbiology
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beta-Lactam Resistance*
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beta-Lactamases / genetics
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beta-Lactamases / metabolism*
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beta-Lactams / therapeutic use
Substances
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Anti-Bacterial Agents
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Carbapenems
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beta-Lactams
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Fosfomycin
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beta-Lactamases
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beta-lactamase NDM-1
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Ertapenem