Torsade de pointes induced by citalopram and amiodarone

Ann Cardiol Angeiol (Paris). 2011 Jun;60(3):165-8. doi: 10.1016/j.ancard.2010.12.002. Epub 2011 Jan 20.

Abstract

Long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by a prolonged QT interval on the electrocardiogram (ECG). This disorder is associated with an increased risk of torsade de pointes (TdP). We report a case of TdP induced by citalopram, a selective serotonin reuptake inhibitor (SSRI), taken in conjunction with amiodarone.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Amiodarone / adverse effects*
  • Amiodarone / therapeutic use
  • Anti-Arrhythmia Agents / adverse effects*
  • Anti-Arrhythmia Agents / therapeutic use
  • Atrial Fibrillation / drug therapy*
  • Citalopram / adverse effects*
  • Citalopram / therapeutic use
  • Depressive Disorder / drug therapy*
  • Diagnosis, Differential
  • Drug Interactions
  • Electrocardiography / drug effects
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Long QT Syndrome / chemically induced
  • Long QT Syndrome / diagnosis
  • Selective Serotonin Reuptake Inhibitors / adverse effects*
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Torsades de Pointes / chemically induced*
  • Torsades de Pointes / diagnosis

Substances

  • Anti-Arrhythmia Agents
  • Serotonin Uptake Inhibitors
  • Citalopram
  • Amiodarone