Identification of a novel HLA-B allele, B*56:31, by sequence-based typing in a Lithuanian individual

Tissue Antigens. 2011 Mar;77(3):262-3. doi: 10.1111/j.1399-0039.2010.01619.x.

Abstract

A novel allele HLA-B*56:31 differs from HLA-B*56:18 by three nucleotide substitutions resulting in a missense mutation Tyr171His (TAC to CAC) encoded in exon 3 and two silent substitutions at codon 188His (CAC to CAT) and codon 228Thr (ACT to ACC) encoded in exon 4.

Publication types

  • Case Reports

MeSH terms

  • Alleles
  • Base Sequence
  • HLA-B Antigens / genetics*
  • Histocompatibility Testing / methods*
  • Humans
  • Lithuania
  • Male
  • Molecular Sequence Data
  • Polymorphism, Genetic
  • Sequence Analysis, DNA / methods*
  • Sequence Homology

Substances

  • HLA-B Antigens