[Pyoderma gangrenosum: spontaneous healing after early diagnosis. Three cases and general review]

Ann Chir Plast Esthet. 2013 Apr;58(2):146-51. doi: 10.1016/j.anplas.2011.01.001. Epub 2011 Feb 11.
[Article in French]

Abstract

Introduction: Pyoderma gangrenosum (PG) is a rare chronic inflammatory skin disease characterized by the recurring development of necrotizing and painful ulcers and therefore, often misinterpreted. This condition can simulate fulminant infection, particularly after surgery. The presentation is often impressive in extensive ulcerations and scarring and lead to significant sequelae. A rapid initial management avoids a dramatic evolution.

Patients and methods: We report the case of three PG for patients followed for breast reconstruction after breast cancer.

Discussion: PG is a neutrophilic dermatosis that can occur after injuries of varying intensity. Its shape after surgery is a rare disease whose presentation loud and fast pace "infectious" contrasts with the absence of inflammatory lymphangitis or lymphadenopathy. Be aware of prescribing high doses of corticosteroids.

Conclusion: These three cases illustrate the importance for early diagnosis and treatment of PG, who can allow spontaneous healing without complex surgery, always feared in this context.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Early Diagnosis
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Mammaplasty / adverse effects*
  • Middle Aged
  • Pyoderma Gangrenosum / diagnosis*
  • Pyoderma Gangrenosum / drug therapy
  • Pyoderma Gangrenosum / etiology
  • Risk Factors
  • Treatment Outcome

Substances

  • Glucocorticoids