Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation

L Rosow; J X Jiang; T Deuel; M Lechpammer; A A Zamani; D A Milner; R Folkerth; F M Marty; S Kesari

doi:10.1111/j.1399-3062.2011.00610.x

Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation

Transpl Infect Dis. 2011 Aug;13(4):419-23. doi: 10.1111/j.1399-3062.2011.00610.x. Epub 2011 Feb 15.

Authors

L Rosow¹, J X Jiang, T Deuel, M Lechpammer, A A Zamani, D A Milner, R Folkerth, F M Marty, S Kesari

Affiliation

¹ Harvard Medical School, Boston, Massachusetts, USA.

PMID: 21323827
DOI: 10.1111/j.1399-3062.2011.00610.x

Abstract

Phaeohyphomycosis is an increasingly recognized cause of brain abscess in both immunocompetent and immunocompromised hosts. We report a case of cerebral phaeohyphomycosis in a 55-year-old male heart transplant recipient caused by Bipolaris spicifera. We review the literature regarding the pathogenesis, epidemiology, diagnosis, and management of infections with dematiaceous fungi.

Publication types

Case Reports

MeSH terms

Antifungal Agents / therapeutic use
Ascomycota / classification
Ascomycota / drug effects
Ascomycota / isolation & purification*
Brain Abscess / diagnostic imaging
Brain Abscess / drug therapy
Brain Abscess / microbiology*
Cerebral Phaeohyphomycosis / diagnostic imaging
Cerebral Phaeohyphomycosis / drug therapy
Cerebral Phaeohyphomycosis / microbiology*
Heart Transplantation / adverse effects*
Humans
Immunocompromised Host
Magnetic Resonance Imaging
Male
Middle Aged
Mycoses / diagnostic imaging
Mycoses / drug therapy
Mycoses / microbiology*
Pyrimidines / therapeutic use
Radiography
Treatment Outcome
Triazoles / therapeutic use
Voriconazole

Substances

Antifungal Agents
Pyrimidines
Triazoles
Voriconazole