Characterization of 2009 pandemic influenza A (H1N1) virus specimens with a positive hemagglutinin 1 signal in the Luminex xTAG respiratory viral panel assay

J Clin Microbiol. 2011 Apr;49(4):1657-8. doi: 10.1128/JCM.02420-10. Epub 2011 Feb 16.

Abstract

This retrospective review analyzed Luminex xTAG respiratory viral panel (RVP) results for 2009 pandemic influenza A (H1N1) virus specimens. Comparing median fluorescence intensity (MFI) signals for the influenza A virus and hemagglutinin 1 (H1) reactions for specimens with very low positive (MFI < 1,000) or "no-call" H1 results reliably distinguished 2009 H1N1 from seasonal virus.

Publication types

  • Evaluation Study

MeSH terms

  • Hemagglutinin Glycoproteins, Influenza Virus / genetics*
  • Humans
  • Influenza A Virus, H1N1 Subtype / classification*
  • Influenza A Virus, H1N1 Subtype / genetics
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human / diagnosis*
  • Influenza, Human / virology*
  • Microarray Analysis / methods*
  • Molecular Diagnostic Techniques / methods
  • Retrospective Studies
  • Sensitivity and Specificity
  • Virology / methods*

Substances

  • Hemagglutinin Glycoproteins, Influenza Virus