Perfluoroalkyl acids including perfluorooctane sulfonate and perfluorohexane sulfonate in firefighters

J Occup Environ Med. 2011 Mar;53(3):324-8. doi: 10.1097/JOM.0b013e31820d1314.

Abstract

Objective: Firefighters were likely exposed to perfluorooctane sulfonate since it was a component of extinguishing foams and perfluorohexane sulfonate (PFHxS), a surfactant coating carpet and other building materials, during firefighting. The objective of the study is to evaluate serum concentrations of perfluoroalkyl acids (PFAAs) in firefighters.

Methods: A total of 8826 male adults, including 37 firefighters, were analyzed. Multivariate analysis was conducted by using a general linear model. The least square mean of serum PFAAs was obtained after adjustment for demographic and socioeconomic variables.

Results: Serum concentration of PFHxS was statistically higher in firefighters both before and after adjustment. Perfluorooctane sulfonate and perfluorononanoic acid were also found higher in firefighters, though not statistically significant.

Conclusions: The study suggests that fighting fire can be a risk of exposure to PFAAs, specifically PFHxS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alkanesulfonic Acids / blood*
  • Caprylates / blood
  • Cross-Sectional Studies
  • Fire Extinguishing Systems
  • Fires*
  • Fluorocarbons / blood*
  • Health Surveys
  • Humans
  • Linear Models
  • Male
  • Multivariate Analysis
  • Occupational Exposure / analysis*
  • Sulfonic Acids / blood*
  • Surface-Active Agents / analysis*

Substances

  • Alkanesulfonic Acids
  • Caprylates
  • Fluorocarbons
  • Sulfonic Acids
  • Surface-Active Agents
  • perfluorohexanesulfonic acid
  • hexadecafluoro-nonanoic acid
  • perfluorooctanoic acid
  • perfluorooctane sulfonic acid