Laboratory characteristics of suspected herpes zoster in vaccinated children

Pediatr Infect Dis J. 2011 Aug;30(8):719-21. doi: 10.1097/INF.0b013e3182137e35.

Abstract

Varicella vaccination of children has decreased varicella disease incidence, but introduced the occurrence of herpes zoster (HZ) from vaccine-type virus. We identified 14 vaccinated children with suspected HZ and confirmed varicella virus by polymerase chain reaction in 6 cases. Two cases were due to vaccine-type virus. Serum varicella IgM and IgG were not useful for diagnosis of HZ among vaccinated children.

MeSH terms

  • Adolescent
  • Antibodies, Viral / blood
  • Chickenpox Vaccine / administration & dosage*
  • Chickenpox Vaccine / adverse effects*
  • Child
  • Child, Preschool
  • DNA, Viral / genetics
  • DNA, Viral / isolation & purification
  • Female
  • Herpes Zoster / diagnosis*
  • Herpesvirus 3, Human / isolation & purification*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Male
  • Polymerase Chain Reaction

Substances

  • Antibodies, Viral
  • Chickenpox Vaccine
  • DNA, Viral
  • Immunoglobulin G
  • Immunoglobulin M