Abstract
A 73-year-old man was referred to our hospital with sigmoid colon cancer in July 2009. CT and MRI showed synchronous multiple liver metastasis. After a sigmoid colon resection in August, he received convergent chemotherapy in combination with 5-fluorouracil(5-FU)/Leucovorin(LV)(RPMI regimen)and bevacizumab for liver metastasis. After two courses without any major adverse effects, liver metastasis remarkably reduced on CT and MRI examination. We thus performed a liver resection, and pathological examination revealed a complete response in liver. Combination chemotherapy of 5-FU/LV and bevacizumab can be expected to provide safe and effective treatment for liver metastasis of colon cancer.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Antibodies, Monoclonal / administration & dosage
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Antibodies, Monoclonal / therapeutic use*
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Antibodies, Monoclonal, Humanized
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bevacizumab
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Combined Modality Therapy
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Fluorouracil / administration & dosage
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Fluorouracil / therapeutic use*
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Humans
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Leucovorin / administration & dosage
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Leucovorin / therapeutic use*
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Liver Neoplasms / drug therapy*
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Liver Neoplasms / secondary
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Liver Neoplasms / surgery
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Magnetic Resonance Imaging
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Male
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Remission Induction
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Sigmoid Neoplasms / drug therapy*
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Sigmoid Neoplasms / pathology*
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Sigmoid Neoplasms / surgery
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Tomography, X-Ray Computed
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Bevacizumab
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Leucovorin
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Fluorouracil