Abstract
Depression has been previously associated with immunologic dysfunction. The lymphocyte subsets of 10 patients with major depression were found to show a mean T4-T8 (helper-suppressor) ratio lower than that of controls, a difference attributable to increased numbers of suppressor cells in the depressed group. One possible cause of increased suppressor cells is prior or current viral infection.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Depressive Disorder / complications
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Depressive Disorder / immunology*
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Female
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Flow Cytometry
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Humans
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Leukocyte Count
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Lymphocytosis / classification
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Lymphocytosis / immunology*
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Male
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Middle Aged
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Pilot Projects
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T-Lymphocytes, Helper-Inducer / immunology*
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T-Lymphocytes, Regulatory / immunology*
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Virus Diseases / complications
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Virus Diseases / immunology