A prospective cohort study was conducted to examine lipid metabolic parameters in 5-14-year-old children. A directional trend was established in lipid parameters (a reduction in the level of total cholesterol and a change in its fractional composition: higher levels of high-density lipoprotein cholesterol with a parallel decrease in the concentration of low-density lipoprotein cholesterol), which is due to age-related features. There was a change in the spread of deviations in cholesterol exchange parameters from the standard values with age.