Sleep hypoventilation syndrome and respiratory failure due to multifocal motor neuropathy with conduction block

Muscle Nerve. 2011 Apr;43(4):610-4. doi: 10.1002/mus.21994.

Abstract

Sleep hypoventilation syndrome and respiratory failure have been reported in association with a diverse spectrum of neuromuscular disorders. We report a patient with multifocal motor neuropathy with conduction block who presented with sleep hypoventilation, presumably due to bilateral phrenic neuropathy and was initially diagnosed to have obstructive sleep apnea syndrome. Once the correct diagnosis was made the patient was treated successfully with a combination of regular immunoglobulin and bilevel nocturnal ventilation. Delay in the administration of intravenous immunoglobulin resulted in respiratory failure.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Humans
  • Hypoventilation / diagnosis*
  • Hypoventilation / etiology
  • Hypoventilation / physiopathology
  • Male
  • Middle Aged
  • Neural Conduction / physiology*
  • Polyneuropathies / complications
  • Polyneuropathies / diagnosis*
  • Polyneuropathies / physiopathology
  • Polysomnography / methods
  • Respiratory Insufficiency / diagnosis*
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / physiopathology
  • Sleep Wake Disorders / diagnosis*
  • Sleep Wake Disorders / etiology
  • Sleep Wake Disorders / physiopathology
  • Syndrome