Extramedullary spinal ependymoma: a diagnostic challenge and review of the literature

Clin Neurol Neurosurg. 2011 Oct;113(8):661-4. doi: 10.1016/j.clineuro.2011.02.021. Epub 2011 Mar 24.

Abstract

Of the 15 cases of intradural extramedullary ependymomas in the literature, only 3 patients were male. The authors report the fourth case to be diagnosed in a male patient and discuss the pathogenesis, presentation, and treatment of this rare form of ependymoma. These cases most commonly show a similar clinical preoperative course to that of a benign meningioma. Although most instances have been reported in females, hormonal influence may not completely explain this neoplasm's pathogenesis. Close follow-up is warranted because of potential recurrence, metastasis, and anaplastic transformation. An ependymoma should be included in the differential diagnosis of intradural extramedullary tumors.

Publication types

  • Case Reports

MeSH terms

  • Combined Modality Therapy
  • Ependymoma / diagnosis*
  • Ependymoma / radiotherapy
  • Ependymoma / surgery
  • Humans
  • Laminectomy
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Spinal Cord / pathology
  • Spinal Cord / surgery
  • Spinal Cord Neoplasms / diagnosis*
  • Spinal Cord Neoplasms / drug therapy
  • Spinal Cord Neoplasms / surgery