Two amino acid changes located in the alpha 1 domain specify the novel HLA-B*27:67 allele affecting the peptide-binding-site characteristics

Tissue Antigens. 2011 Jun;77(6):599-601. doi: 10.1111/j.1399-0039.2011.01648.x. Epub 2011 Mar 28.

Abstract

The novel HLA-B*27:67 contains three nucleotide substitutions in exon 2 leading to two amino acid changes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Base Sequence
  • Binding Sites
  • Blood Group Incompatibility
  • Exons
  • HLA-B Antigens / chemistry
  • HLA-B Antigens / genetics*
  • Haplotypes
  • Histocompatibility Testing / methods
  • Humans
  • Models, Genetic
  • Molecular Sequence Data
  • Nucleotides / genetics
  • Peptides / chemistry
  • Protein Structure, Tertiary
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid
  • Stem Cells / cytology

Substances

  • HLA-B Antigens
  • Nucleotides
  • Peptides

Associated data

  • GENBANK/FN870366