A method for the deprotection of alkylpinacolyl boronate esters

J Org Chem. 2011 May 6;76(9):3571-5. doi: 10.1021/jo200250y. Epub 2011 Apr 7.

Abstract

A two-step procedure for deprotection of alkylpinacolyl boronate esters via transesterification with diethanolamine followed by hydrolysis was successfully developed with the advantages of tolerance to various functional groups, short reaction time, and ease of product isolation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boronic Acids / chemistry*
  • Esters
  • Hydrolysis

Substances

  • Boronic Acids
  • Esters