Poly(2,3-diaminonaphthalene) microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection

Analyst. 2011 Jun 7;136(11):2221-4. doi: 10.1039/c0an00944j. Epub 2011 Mar 31.

Abstract

In this Communication, we report on the first preparation of conjugation polymer poly(2,3-diaminonaphthalene) (PDAN) microspheres via chemical oxidation polymerization of 2,3-diaminonaphthalene (DAN) monomers by ammonium persulfate (APS) at room temperature. We further demonstrate the use of PDAN microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 2-Naphthylamine / analogs & derivatives*
  • 2-Naphthylamine / chemistry
  • DNA / analysis*
  • Fluorescent Dyes / chemistry
  • Microspheres*
  • Polymers / chemistry*
  • Spectrometry, Fluorescence / methods*
  • Temperature

Substances

  • Fluorescent Dyes
  • Polymers
  • 2,3-diaminonaphthalene
  • DNA
  • 2-Naphthylamine