The British HIV Association national audit on the management of subjects co-infected with HIV and hepatitis B/C

Int J STD AIDS. 2011 Mar;22(3):173-6. doi: 10.1258/ijsa.2010.010380.

Abstract

The aim of this work was to survey current service provision and adherence to the British HIV Association (BHIVA) guidelines for the management of HIV and hepatitis B/C co-infected patients in the UK. Sites were invited to complete a survey of local care arrangements for co-infected patients. A case-note audit of all co-infected attendees during a six-month period in 2009 was performed. Data including demographics, clinical parameters, hepatitis disease status, antiretroviral and hepatitis B/C therapy were collected. Using BHIVA guidelines as audit standards, the proportion of sites and subjects meeting each standard was calculated. One-hundred and forty sites (75%) responded and data from 973 eligible co-infected patients were submitted. Approximately a third of sites reported not re-checking hepatitis serology or vaccination titres annually. Of all co-infected patients, 122 (13%) were neither vaccinated nor immune to hepatitis A and 26 (5%) of patients with hepatitis C were neither vaccinated nor naturally immune to hepatitis B. Of HBsAg-positive subjects, 25 (6%) were receiving lamivudine as the sole drug with antihepatitis B activity. In the UK, the management of HIV and hepatitis B/C co-infection remains highly variable. Optimizing the care of this high-risk patient group is a priority.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Guideline Adherence
  • HIV Infections / epidemiology
  • HIV Infections / therapy*
  • HIV Infections / virology*
  • Health Care Surveys
  • Hepatitis B / epidemiology
  • Hepatitis B / therapy*
  • Hepatitis B / virology*
  • Hepatitis C / epidemiology
  • Hepatitis C / therapy*
  • Hepatitis C / virology*
  • Humans
  • Male
  • Medical Audit
  • United Kingdom / epidemiology
  • Viral Vaccines / administration & dosage

Substances

  • Viral Vaccines