Abstract
We determined minimum inhibitory concentrations of rifampicin, nitrofurantoin, amoxicillin-clavulanic acid, and cefdinir, plus a combination of amoxicillin-clavulanic acid and cefdinir by broth microdilution for mainly wound isolates of Escherichia coli and Klebsiella pneumoniae. E. coli and K. pneumoniae susceptibilities increased by combining amoxicillin-clavulanic acid and cefdinir.
MeSH terms
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Administration, Oral
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Amoxicillin-Potassium Clavulanate Combination / pharmacology
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Anti-Bacterial Agents / pharmacology*
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Cefdinir
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Cephalosporins / pharmacology
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Drug Resistance, Multiple, Bacterial
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Enterobacteriaceae Infections / microbiology*
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Escherichia coli / drug effects*
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Escherichia coli / isolation & purification
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Humans
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Klebsiella pneumoniae / drug effects*
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Klebsiella pneumoniae / isolation & purification
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Microbial Sensitivity Tests
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Nitrofurantoin / pharmacology
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Rifampin / pharmacology
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Wound Infection / microbiology
Substances
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Anti-Bacterial Agents
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Cephalosporins
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Amoxicillin-Potassium Clavulanate Combination
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Nitrofurantoin
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Cefdinir
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Rifampin