Psoralenquinones as a novel class of proteasome inhibitors: design, synthesis and biological evaluation

ChemMedChem. 2011 Jun 6;6(6):996-1000. doi: 10.1002/cmdc.201100041. Epub 2011 Apr 6.
No abstract available

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology*
  • Ficusin / chemistry*
  • Ficusin / pharmacology*
  • Humans
  • Models, Molecular
  • Neoplasms / drug therapy
  • Proteasome Inhibitors*
  • Protein Binding
  • Quinones / chemistry*
  • Quinones / pharmacology*

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Proteasome Inhibitors
  • Quinones
  • Ficusin