Cells producing insulin-like androgenic gland hormone of the giant freshwater prawn, Macrobrachium rosenbergii, proliferate following bilateral eyestalk-ablation

Tissue Cell. 2011 Jun;43(3):165-77. doi: 10.1016/j.tice.2011.02.001. Epub 2011 Apr 8.

Abstract

We found that the androgenic gland (AG) of Macrobrachium rosenbergii possesses three cell types. Type I cells are small polygonal shaped-cells (13.4 μm in diameter), stain strongly with hematoxylin-eosin (H&E), have abundant multilayered rough endoplasmic reticulum (rER), and nuclei containing mostly heterochromatin. Type II cells are slightly larger (18.6 μm in diameter), stain lightly with H&E, have rER with dilated cisternae, and nuclei containing mostly euchromatin. Type III cells (previously undescribed) are similar in size and shape to type I cells, but the cytoplasm is unstained and they have a high amount of smooth endoplasmic reticulum (sER) and mitochondria with tubular cristae. Bilateral eyestalk-ablation resulted in AG hypertrophy with a proliferation and predominance of type I cells as determined by bromodeoxyuridine (BrdU) assays. Expression of insulin-like androgenic gland hormone (Mr-IAG), determined by immunohistochemistry, was weak in type I cells, strong in type II cells of both the intact and eyestalk-ablated, and negative in type III cells. It was also detected in spermatogonia, nurse cells, and epithelium lining of the spermatic duct. The function of Mr-IAG in these tissues is yet to be elucidated but the distribution implies a strong role in male reproduction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Androgens / metabolism
  • Animal Structures / physiology*
  • Animals
  • Cell Nucleus / metabolism
  • Cell Proliferation
  • Endoplasmic Reticulum, Rough / ultrastructure
  • Exocrine Glands / cytology*
  • Exocrine Glands / ultrastructure
  • Eye
  • Invertebrate Hormones / metabolism*
  • Male
  • Mitochondria / metabolism
  • Palaemonidae / metabolism*
  • Somatomedins / biosynthesis*

Substances

  • Androgens
  • Invertebrate Hormones
  • Somatomedins