Neurogenic stunned myocardium presenting as left ventricular hypertrabeculation in childhood: a variant of Takotsubo cardiomyopathy?

Pediatr Crit Care Med. 2011 Nov;12(6):e420-3. doi: 10.1097/PCC.0b013e3182192944.

Abstract

Objective: To report the first case of neurogenic stunned myocardium presenting with heart left ventricle noncompaction requiring intensive care in the perioperative period of tension tumor-induced hydrocephalus.

Methods and design: Case report and literature review. Our Institutional Review Board waived the need for consent.

Patient: A 12-yr-old female with intracranial astrocytoma and hypertensive hydrocephalus presented with severe heart dysfunction and life-threatening ventricular ectopies intraoperatively. A severe heart failure developed requiring hemodynamic and ventilatory support for 10 days. Echocardiography showed a transient noncompaction aspect of the left ventricular wall, further confirmed by a cardiac magnetic resonance image. The noncompaction aspect lasted until 15 days postadmission, as was the case for the QT interval prolongation; no life-threatening ectopies were demonstrated on the subsequent Holter electrocardiogram monitoring.

Conclusions: This report describes a unique presentation of myocardial stunning in association with an intracranial illness, namely, a hypertensive hydrocephalus complicating an intracranial neoplasm.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Astrocytoma / complications
  • Brain Neoplasms / complications
  • Child
  • Diagnosis, Differential
  • Echocardiography
  • Female
  • Heart Ventricles / physiopathology*
  • Humans
  • Hydrocephalus / etiology
  • Hydrocephalus / physiopathology
  • Myocardial Stunning / diagnosis*
  • Myocardial Stunning / physiopathology*
  • Neurosurgery / methods
  • Takotsubo Cardiomyopathy*