Prognostic impact and therapeutic implications of sentinel lymph node micro-metastases in early-stage breast cancer patients

J Surg Oncol. 2011 May 1;103(6):531-3. doi: 10.1002/jso.21693.

Abstract

The prognostic value of sentinel lymph node (SLN) micro-metastases and the question whether patients with SLN micro-metastases should undergo axillary lymph node dissection remain a matter of great debate. Based on the current literature and on our own data, we provide suggestive evidence that SLN micro-metastases in early stage breast cancer patients appear to have prognostic value and should impact the decision-making regarding adjuvant therapy, however, do not necessarily require further surgical treatment.

Publication types

  • Review

MeSH terms

  • Axilla
  • Breast Neoplasms / pathology*
  • Female
  • Humans
  • Lymphatic Metastasis / pathology
  • Neoplasm Recurrence, Local / prevention & control
  • Neoplasm Staging
  • Sentinel Lymph Node Biopsy*
  • Treatment Outcome