Should we still be focused on red cell hemoglobin F as the principal explanation for the salutary effect of hydroxyurea in sickle cell disease?

Pediatr Blood Cancer. 2011 Jul 15;57(1):8-9. doi: 10.1002/pbc.23128. Epub 2011 Apr 7.
No abstract available

Publication types

  • Comment

MeSH terms

  • Adolescent
  • Anemia, Sickle Cell / blood*
  • Anemia, Sickle Cell / pathology*
  • Anemia, Sickle Cell / therapy
  • Antisickling Agents / therapeutic use
  • Blood Transfusion
  • Child
  • Child, Preschool
  • Erythrocyte Count
  • Erythrocytes, Abnormal / pathology*
  • Fetal Hemoglobin / analysis*
  • Humans
  • Hydroxyurea / therapeutic use
  • Infant
  • Young Adult

Substances

  • Antisickling Agents
  • Fetal Hemoglobin
  • Hydroxyurea