Ultrasonographic assessment of colonic wall in moderate-severe ulcerative colitis: comparison with endoscopic findings

Dig Liver Dis. 2011 Sep;43(9):703-6. doi: 10.1016/j.dld.2011.02.019. Epub 2011 Apr 8.

Abstract

Background: Bowel ultrasound has been shown to be a useful tool to evaluate patients with inflammatory bowel disease, especially Crohn's disease. However, such data are still scarce in ulcerative colitis patients.

Aims: To establish the value of bowel ultrasound in moderate to severe ulcerative colitis patients, and compare these data with endoscopic findings.

Patients and methods: Endoscopic, ultrasound and C-reactive protein data from 51 patients with moderate to severe ulcerative colitis observed during a 3-year period were retrospectively obtained and analysed.

Results: All patients displayed pathological thickness (>4 mm) of the colon wall. This value strongly correlated with C-reactive protein values (p=0.0001) and the endoscopic score (p<0.0001). Also, a strong correlation (p<0.0001) was found between CRP values and endoscopic score.

Conclusions: Bowel ultrasound, in expert hands, may represent a useful adjunctive (or first line) tool for the evaluation of patients with moderate to severe ulcerative colitis.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • C-Reactive Protein / metabolism
  • Colitis, Ulcerative / diagnostic imaging*
  • Colitis, Ulcerative / metabolism
  • Colitis, Ulcerative / pathology*
  • Colon / diagnostic imaging*
  • Colon / pathology*
  • Colonoscopy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Severity of Illness Index
  • Ultrasonography
  • Young Adult

Substances

  • C-Reactive Protein