Does 24-h urinary MHPG predict treatment response to antidepressants? I. A review

M Garvey; S D Hollon; R J DeRubeis; M D Evans; V B Tuason

doi:10.1016/0165-0327(90)90141-t

Does 24-h urinary MHPG predict treatment response to antidepressants? I. A review

J Affect Disord. 1990 Nov;20(3):173-9. doi: 10.1016/0165-0327(90)90141-t.

Authors

M Garvey¹, S D Hollon, R J DeRubeis, M D Evans, V B Tuason

Affiliation

¹ Department of Psychiatry, University of Iowa College of Medicine, Iowa City.

PMID: 2148337
DOI: 10.1016/0165-0327(90)90141-t

Abstract

The ability of pretreatment 3-methoxy-4-hydroxyphenylglycol (MHPG) to predict response to various antidepressants is reviewed. MHPG appears to be a modest predictor of treatment response to imipramine but does not appear to be a reliable predictor for other antidepressants.

Publication types

Review

MeSH terms

Antidepressive Agents / therapeutic use*
Depressive Disorder / drug therapy*
Depressive Disorder / psychology
Depressive Disorder / urine
Humans
Methoxyhydroxyphenylglycol / urine*

Substances

Antidepressive Agents
Methoxyhydroxyphenylglycol