Esomeprazole but not pantoprazole is associated with lower plasma concentrations of clopidogrel's active metabolite

Ann Pharmacother. 2011 Apr;45(4):542-3. doi: 10.1345/aph.1P425. Epub 2011 Apr 12.
No abstract available

Publication types

  • Letter

MeSH terms

  • 2-Pyridinylmethylsulfinylbenzimidazoles / adverse effects
  • 2-Pyridinylmethylsulfinylbenzimidazoles / pharmacology*
  • Clopidogrel
  • Drug Interactions
  • Enzyme Inhibitors / adverse effects
  • Enzyme Inhibitors / pharmacology
  • Esomeprazole / adverse effects
  • Esomeprazole / pharmacology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pantoprazole
  • Platelet Aggregation Inhibitors / blood
  • Platelet Aggregation Inhibitors / pharmacokinetics
  • Platelet Aggregation Inhibitors / pharmacology
  • Proton Pump Inhibitors / adverse effects
  • Proton Pump Inhibitors / pharmacology
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / blood
  • Ticlopidine / pharmacokinetics
  • Ticlopidine / pharmacology

Substances

  • 2-Pyridinylmethylsulfinylbenzimidazoles
  • Enzyme Inhibitors
  • Platelet Aggregation Inhibitors
  • Proton Pump Inhibitors
  • Clopidogrel
  • Pantoprazole
  • Esomeprazole
  • Ticlopidine