LY233053: a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist

Prog Clin Biol Res. 1990:361:429-33.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Binding, Competitive
  • Brain / cytology
  • Brain / drug effects
  • Dose-Response Relationship, Drug
  • Kinetics
  • Mice
  • N-Methylaspartate / toxicity
  • Neurons / drug effects
  • Neurons / physiology
  • Pipecolic Acids / metabolism
  • Pipecolic Acids / pharmacology*
  • Rats
  • Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
  • Receptors, N-Methyl-D-Aspartate / metabolism
  • Seizures / chemically induced
  • Seizures / drug therapy
  • Tetrazoles / metabolism
  • Tetrazoles / pharmacology*

Substances

  • Pipecolic Acids
  • Receptors, N-Methyl-D-Aspartate
  • Tetrazoles
  • LY 233053
  • N-Methylaspartate