Induced polymersome formation from a diblock PS-b-PAA polymer via encapsulation of positively charged proteins and peptides

David Hvasanov; Jörg Wiedenmann; Filip Braet; Pall Thordarson

doi:10.1039/c1cc11662b

Induced polymersome formation from a diblock PS-b-PAA polymer via encapsulation of positively charged proteins and peptides

Chem Commun (Camb). 2011 Jun 14;47(22):6314-6. doi: 10.1039/c1cc11662b. Epub 2011 Apr 21.

Authors

David Hvasanov¹, Jörg Wiedenmann, Filip Braet, Pall Thordarson

Affiliation

¹ School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.

PMID: 21512714
DOI: 10.1039/c1cc11662b

Abstract

In contrast to simple salts or negatively charged macromolecules, positively charged proteins and peptides including cytochrome c (yeast) and poly-L-lysine are efficiently encapsulated while inducing the formation of polymersomes from polystyrene(140)-b-poly(acrylic acid)(48) (PS(140)-b-PAA(48)).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acrylates / chemistry
Capsules / chemistry*
Cytochromes c / chemistry*
Green Fluorescent Proteins / chemistry
Peptides / chemistry*
Polylysine / chemistry
Polystyrenes / chemistry

Substances

Acrylates
Capsules
Peptides
Polystyrenes
poly(styrene-b-acrylic acid)
Green Fluorescent Proteins
Polylysine
Cytochromes c