Lack of evidence for systemic cytomegalovirus reactivation in maintenance hemodialysis patients

Eur J Clin Microbiol Infect Dis. 2011 Dec;30(12):1557-60. doi: 10.1007/s10096-011-1260-8. Epub 2011 Apr 26.

Abstract

The risk of cytomegalovirus (CMV) reactivation among hemodialysis (HD) patients is unknown. In 52 HD patients from a single center, CMV serology and quantitative PCR were performed. The detection limit of PCR was 20 copies/ml. Here, PCR ruled out CMV viremia, despite CMV-IgM seropositivity in 15.4% patients.

MeSH terms

  • Cytomegalovirus / genetics
  • Cytomegalovirus / immunology
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / epidemiology*
  • Cytomegalovirus Infections / virology*
  • Humans
  • Middle Aged
  • Polymerase Chain Reaction
  • Renal Dialysis / adverse effects*
  • Renal Dialysis / methods*
  • Serologic Tests
  • Viremia / diagnosis
  • Virus Activation*