The discovery of MMP7 inhibitors exploiting a novel selectivity trigger

MeSH terms

• Amino Acid Sequence
• Binding Sites
• Catalytic Domain
• Computer Simulation
• Crystallography, X-Ray
• Drug Evaluation, Preclinical
• High-Throughput Screening Assays
• Matrix Metalloproteinase 7 / metabolism
• Matrix Metalloproteinase Inhibitors*
• Molecular Sequence Data
• Protease Inhibitors / chemical synthesis
• Protease Inhibitors / chemistry*
• Protease Inhibitors / pharmacology
• Sequence Alignment