[Severe hyponatremia in acute porphyria. Central pontine myelinolysis as a complication of its treatment]

Rev Med Chil. 1990 Oct;118(10):1129-34.
[Article in Spanish]

Abstract

Two patients developed severe hyponatremia attributed to inappropriate antidiuretic hormone secretion during a crisis of acute porphyria, and were treated with intravenous hypertonic sodium solution. One of them developed clinical and radiological findings of pontine and extrapontine myelinolysis, which may constitute a risk in the treatment of this complication.

Publication types

  • Case Reports
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Brain Diseases / diagnosis
  • Brain Diseases / etiology*
  • Demyelinating Diseases / diagnosis
  • Demyelinating Diseases / etiology*
  • Female
  • Humans
  • Hyponatremia / complications
  • Hyponatremia / diagnosis
  • Hyponatremia / etiology*
  • Hyponatremia / therapy
  • Inappropriate ADH Syndrome / complications
  • Pons*
  • Porphyrias / complications*
  • Porphyrias / diagnosis
  • Porphyrias / therapy
  • Porphyrins / analysis

Substances

  • Porphyrins