Purine metabolism, immune reconstitution, and abdominal adipose tumor after gene therapy for adenosine deaminase deficiency

J Allergy Clin Immunol. 2011 Jun;127(6):1417-9.e3. doi: 10.1016/j.jaci.2011.04.014. Epub 2011 Apr 29.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Neoplasms / etiology*
  • Abdominal Neoplasms / genetics
  • Adenosine Deaminase / deficiency
  • Adenosine Deaminase / immunology
  • Adenosine Deaminase / metabolism
  • Agammaglobulinemia / complications
  • Agammaglobulinemia / immunology
  • Agammaglobulinemia / metabolism
  • Agammaglobulinemia / therapy
  • Child, Preschool
  • Chromosome Banding
  • Chromosomes, Human, Pair 19 / genetics
  • Chromosomes, Human, Pair 8 / genetics
  • Genetic Therapy / adverse effects*
  • Humans
  • Lipoma / etiology*
  • Lipoma / genetics
  • Male
  • Purines / metabolism
  • Severe Combined Immunodeficiency / complications
  • Severe Combined Immunodeficiency / immunology
  • Severe Combined Immunodeficiency / metabolism
  • Severe Combined Immunodeficiency / therapy
  • Translocation, Genetic

Substances

  • Purines
  • Adenosine Deaminase

Supplementary concepts

  • Severe combined immunodeficiency due to adenosine deaminase deficiency