Snoring is not associated with adverse effects on blood pressure, arterial structure or function in 8-year-old children: the Childhood Asthma Prevention Study (CAPS)

J Paediatr Child Health. 2011 Aug;47(8):518-23. doi: 10.1111/j.1440-1754.2011.02014.x. Epub 2011 Apr 29.

Abstract

Aims: To study the association between childhood snoring and cardiovascular risk factors.

Methods: Cross-sectional analyses of a population-based birth cohort, who had been participants in a randomised controlled trial of interventions to prevent asthma and who were assessed at age 8 years. The presence and frequency of snoring were assessed by parent-completed questionnaire. We measured a wide range of cardiovascular function markers including non-fasting serum lipoproteins, blood pressure, high-sensitivity C-reactive protein, carotid artery intima media thickness (by ultrasound), brachial pulse wave velocity and augmentation index (by applanation tonometry).

Results: Of 409 children whose snoring status was assessed at age 8 years, 321 had lipid and 386 had arterial structure and function measurements. Snoring was not independently associated with blood pressure, carotid artery intima media thickness or measures of arterial stiffness (all P > 0.05). Increasing snoring frequency was independently associated with lower high-density lipoprotein cholesterol (-0.032 g/dL per step, 95% confidence interval -0.060 to -0.003), although the difference in high-density lipoprotein between snorers and non-snorers was not significant (P = 0.052). An association of snoring frequency with brachial pulse wave velocity differed according to body mass index (P = 0.03) and was the reverse of that expected.

Conclusions: Parentally reported snoring was not independently associated with adverse measurements of metabolic markers, vascular structure or function in 8-year-old children. Parental reports of snoring may be below the treatment threshold without additional diagnosis via sleep studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asthma / prevention & control
  • Blood Pressure / physiology
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / etiology*
  • Cardiovascular Diseases / physiopathology
  • Carotid Arteries / diagnostic imaging
  • Child
  • Cholesterol, HDL / blood
  • Cross-Sectional Studies
  • Female
  • Humans
  • Linear Models
  • Male
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Snoring / complications*
  • Surveys and Questionnaires
  • Tunica Intima / diagnostic imaging
  • Ultrasonography

Substances

  • Cholesterol, HDL