Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia

Leukemia. 2011 Aug;25(8):1365-8. doi: 10.1038/leu.2011.86. Epub 2011 May 3.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Down Syndrome / blood
  • Down Syndrome / genetics*
  • Down Syndrome / mortality
  • Female
  • Humans
  • Janus Kinase 1 / genetics*
  • Janus Kinase 2 / genetics*
  • Janus Kinase 3 / genetics*
  • Leukemia, Myeloid / blood
  • Leukemia, Myeloid / genetics*
  • Leukemia, Myeloid / mortality
  • Leukocyte Count
  • Male
  • Mutation*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • Prognosis

Substances

  • JAK1 protein, human
  • JAK2 protein, human
  • JAK3 protein, human
  • Janus Kinase 1
  • Janus Kinase 2
  • Janus Kinase 3