Progestins possess poor anti-estrogenic activity on murine hepatic coagulation gene transcription despite evident anti-estrogenic activity on uterine tissue

Thromb Res. 2011 Aug;128(2):200-1. doi: 10.1016/j.thromres.2011.04.008. Epub 2011 May 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Coagulation / drug effects
  • Blood Coagulation / genetics*
  • Contraceptives, Oral / pharmacology
  • Desogestrel / pharmacology*
  • Estrogen Antagonists / pharmacology*
  • Ethinyl Estradiol / pharmacology
  • Female
  • Humans
  • Levonorgestrel / pharmacology*
  • Liver / drug effects*
  • Liver / metabolism
  • Liver / physiology
  • Mice
  • Mice, Inbred C57BL
  • Receptors, Estrogen / metabolism
  • Receptors, Progesterone / metabolism
  • Transcription, Genetic / drug effects
  • Uterus / drug effects*

Substances

  • Contraceptives, Oral
  • Estrogen Antagonists
  • Receptors, Estrogen
  • Receptors, Progesterone
  • Ethinyl Estradiol
  • Levonorgestrel
  • Desogestrel