Dyslipidemia as a long-term marker for survival in pulmonary embolism

L Jara-Palomares; R Otero-Candelera; T Elias-Hernandez; A Cayuela-Dominguez; M Ferrer-Galvan; M J Alfaro; E Montero; E Barrot-Cortes

doi:10.1016/j.rppneu.2011.03.006

Dyslipidemia as a long-term marker for survival in pulmonary embolism

Rev Port Pneumol. 2011 Sep-Oct;17(5):205-10. doi: 10.1016/j.rppneu.2011.03.006. Epub 2011 Apr 29.

Authors

L Jara-Palomares¹, R Otero-Candelera, T Elias-Hernandez, A Cayuela-Dominguez, M Ferrer-Galvan, M J Alfaro, E Montero, E Barrot-Cortes

Affiliation

¹ Medical-Surgical Unit of Respiratory Diseases, University Hospital Virgen del Rocio, Seville, Spain. [email protected]

PMID: 21549676
DOI: 10.1016/j.rppneu.2011.03.006

Abstract

Objectives: To analyse survival rate after 24 months in consecutive patients with a diagnosis of PE as well as associated factors.

Methods: Prospective cohort study during a follow-up period of two years in a series of consecutive patients with PE.

Results: During the follow-up period, 34 out of 148 patients died (23%). Factors independently associated with reduced survival rate were: creatinine levels > 2 (OR, 8.8; 95% CI, 1.1 - 70.87), previous neoplasm (OR, 8.8; 95% CI, 3.69 - 20.98), dementia (OR, 6.85; 95% CI, 2.1 - 22.33) and dyslipidemia (OR, 5.07; 95% CI, 1.92 - 13.44). Forty four percent of the patients with dyslipidemia died vs. 20.8% of patients without this condition.

Conclusions: In our study dyslipidemia shows as a long-term negative prognostic marker for survival in patients with EP.

MeSH terms

Aged
Dyslipidemias / etiology*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Prognosis
Prospective Studies
Pulmonary Embolism / complications
Pulmonary Embolism / mortality*
Survival Rate
Time Factors